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目的分析肺炎支原体肺炎(MPP)肺外器官受累的发生状况,了解肺炎支原体(MP)感染所致多器官损害的特点,探讨小儿MPP合并肺外器官损害的临床特征及其发生的可能机制,为临床医师认识该疾病提供理论依据,指导临床医师的诊断、治疗。方法回顾性分析自2010年9月-2012年6月期间在小儿内科接受治疗的98例感染MP的患儿,观察MP肺炎患儿肺外器官损害的临床表现,对结果进行统计。结果 98例MP感染患儿中59例(60.2%)患儿存在肺外器官受累,其中以心血管、血液、消化、神经系统多见,皮肤黏膜、泌尿系统少见。13例(13.26%)患儿同时发生多个肺外器官受累,病情较重,还有2例(2.04%)患儿以肺外并发症为首发症状,易造成漏诊、误诊,应及时检测血清支原体抗体。结论 MP感染在小儿合并肺外器官受累具有普遍性,除造成呼吸道损害外,尚可引起其他多脏器、多系统的损害,损害大多症状轻,恢复快,预后好。故在治疗MP感染的同时,除了积极治疗原发病,要密切观察是否存在肺外器官损害,防治严重并发症,应引起临床医师的足够重视。
Objective To analyze the occurrence of extrapulmonary organ involvement in Mycoplasma pneumoniae pneumonia (MPP), understand the characteristics of multiple organ damage caused by Mycoplasma pneumoniae (MP) infection and to explore the clinical features and possible mechanism of MPP complicated with extrapulmonary organ damage in children Clinicians to understand the disease provide a theoretical basis to guide the clinician’s diagnosis and treatment. Methods A retrospective analysis of 98 infants with MP who were treated in pediatric medicine from September 2010 to June 2012 was performed to observe the clinical manifestations of extrapulmonary organ damage in children with MP pneumonia and the results were statistically analyzed. Results Of the 98 children with MP infection, 59 cases (60.2%) had extrapulmonary organ involvement. Among them, cardiovascular, blood, digestive and nervous system were more common. Skin and mucous membranes and urinary system were rare. Thirteen (13.26%) children suffered multiple extrapulmonary organ involvement at the same time and their condition was severe. Two children (2.04%) had extrapulmonary complication as the first symptom, which could easily lead to missed diagnosis and misdiagnosis. Serum should be detected in time Mycoplasma antibody. Conclusion MP infection in children with extrapulmonary organ involvement is common, in addition to causing respiratory damage, it can cause other multi-organ, multi-system damage, damage to most symptoms, rapid recovery, good prognosis. Therefore, in the treatment of MP infection at the same time, in addition to active treatment of the primary disease, to observe closely the existence of extrapulmonary organ damage, prevention and treatment of serious complications, clinicians should cause enough attention.