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We numerical simulate the propagation behaviour and people distribution trait of epidemic spreading in mobile individuals by using cellular automaton method.The simulation results show that there exists a critical value of infected rate fluctuating amplitude,above which the epidemic can spread in whole population.Moreover,with the value of infected rate fluctuating amplitude increasing,the spatial distribution of infected population exhibits the spontaneous formation of irregular spiral waves and convergence phenomena,at the same time,the density of different populations will oscillate automatically with time.What is more,the traits of dynamic grow clearly and stably when the time and the value of infected rate fluctuating amplitude increasing.It is also found that the maximal proportion of infected individuals os independent of the value of fluctuating amplitude rate,but increases linearly with the population density.