视网膜母细胞瘤是婴幼儿最常见的眼内恶性肿瘤,以单眼发病为多,约18%～40%可双眼发病[1]。三侧性视网膜母细胞瘤(trilateral retinoblastoma)罕见,现报道1例如下:病例患者女,2岁。因左眼视力丧失,右眼视力减退就诊。眼科检查:双眼可见“猫眼”征,眼底镜检查双眼玻璃体内有椭圆 Retinoblastoma is the most common intraocular malignant tumor in infants and young children, the incidence of monocular more, about 18% to 40% of binocular onset [1]. Trilateral retinoblastoma rare, reported 1 cases are reported as follows: Female patients, 2 years of age. Due to loss of left eye vision, vision loss of right eye treatment. Eye examination: both eyes can be seen “cat’s eye” sign, ophthalmoscopy binocular vitreous oval