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宫颈癌是唯一病因明确,可预防的恶性肿瘤,因而宫颈癌的早期筛查意义深远。目前,宫颈癌初筛检查项目包括:宫颈人乳头瘤病毒(HPV)分型检测及宫颈液基细胞学(TCT)检查,然而,大多数患者宫颈HPV常常为一过性感染,数月后可转阴,且细胞异型性通常会自行消失,进展为宫颈癌者寥寥无几。因其灵敏度高,特异性较低,临床常出现过度诊治,同时还会造成患者的心理恐慌,增加患者的经济负担,因此寻找更有效的宫颈癌筛查方法成为关注的焦点。
Cervical cancer is the only clear cause of prevention of malignant tumors, and therefore early screening of cervical cancer is of far-reaching significance. Currently, cervical cancer screening tests include: cervical HPV testing and cervical liquid-based cytology (TCT) examination, however, most patients with cervical HPV is often a transient infection, a few months later Negative, and cellular atypia usually disappear, progress to cervical cancer are few. Because of its high sensitivity, low specificity, frequent clinical diagnosis and treatment, but also cause the patient’s psychological panic and increase the economic burden on patients, so to find more effective screening methods for cervical cancer has become the focus of attention.