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Fas和Fas配体(FasL)是已认识到的一对诱导细胞凋亡的膜蛋白分子,它们之间构成一条独特的细胞凋亡通路。本文对FasL的分子生物学特性和生理功能及其在疾病发生中的作用作一综述。
Fas and Fas ligand (FasL) are a pair of membrane-associated molecules that induce apoptosis, forming a unique apoptotic pathway between them. This article reviews the molecular biological characteristics and physiological functions of FasL and its role in the pathogenesis of diseases.