药物所致的肺部疾病主要表现以下几方面。1支气管痉挛 青霉素、磺胺药、血清制品引起支气管痉挛,多为I型变态反应。气道反应性增高的患者使用普萘洛尔(心得安)、新斯的明或雾化吸入异丙肾上腺素、色甘酸钠、乙酰半胱氨酸(痰易净)等,可诱发或加重支气管痉挛。非甾体抗炎药也可诱发支气管痉挛,其机制与影响前列腺素的代谢有关。2呼吸中枢抑制2.1 吗啡制剂有明显的呼吸中枢抑制作用,当与地西泮、硫喷妥钠、硫酸镁合用时,更易引起呼吸中枢抑制。大剂量快速静脉 Pulmonary diseases caused by drugs mainly in the following aspects. 1 bronchospasm penicillin, sulfa drugs, serum products caused by bronchospasm, mostly I-type allergy. Patients with increased airway responsiveness may be induced or exacerbated by propranolol (propranolol), neostigmine or nebulized isoproterenol, cromolyn sodium, acetylcysteine ​​(phlegm-easy net), etc. Bronchospasm. Non-steroidal anti-inflammatory drugs can also induce bronchospasm, the mechanism of which is related to the metabolism of prostaglandins. 2 respiratory center inhibition 2.1 morphine preparations have obvious respiratory center inhibition, when combined with diazepam, thiopental, magnesium sulfate, more likely to cause respiratory depression. High-dose rapid vein