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目的探讨伴有肥胖基础的甲型H1N1流感临床特征,为制定诊疗方案提供科学依据。方法回顾分析2009年6月至2010年3月住院的伴有肥胖基础的甲型H1N1流感患者(肥胖组)42例的临床资料,并与同期住院的无肥胖基础的甲型H1N1流感患者(非肥胖组)72例的临床资料进行比较分析。结果伴有肥胖基础的甲型H1N1流感组患者的病程、发热时间、胸闷胸痛、肺部啰音、C-反应蛋白(C-creactive protein,CRP)水平、心肌酶谱上升例数、并发肺炎的发生率高于无肥胖基础的甲型H1N1流感组患者,差异有统计学意义(P<0.05);两组间咳嗽、咽痛、流涕、头痛、胃肠道症状发生率,血常规、肝肾功能等差异均无统计学意义(P>0.05)。结论伴有肥胖基础的甲型H1N1流感临床表现重于无肥胖基础的甲型H1N1流感患者。
Objective To investigate the clinical features of influenza A (H1N1) associated with obesity and provide a scientific basis for formulating diagnosis and treatment plans. Methods The clinical data of 42 patients with obesity-based H1N1 influenza (obesity group) hospitalized from June 2009 to March 2010 in our hospital were retrospectively analyzed. They were compared with those of the non-fat-based H1N1 influenza patients Obese group) 72 cases of clinical data for comparative analysis. Results The course of disease, fever time, chest pain, pulmonary rales, C-creactive protein (CRP) level, the number of myocardial enzymes increased, pneumonia (P <0.05). The incidence of cough, sore throat, runny nose, headache, the incidence of gastrointestinal symptoms, blood routine, liver and liver disease in both groups were significantly higher than those in the non-obese group There was no significant difference in renal function (P> 0.05). Conclusions The clinical manifestations of influenza A (H1N1) with obesity are more severe than those without underlying obesity.