治疗δ感染受制于抗病毒药。Thomas使用1千万单位/m~2 的类淋巴母细胞的α-干扰素,每周3次给5例δ感染的慢性活动性肝炎或肝硬变患者治疗12周。3例显示血清肝脏δ RNA 消失的完全反应;1例有部分降低,但 HDV-RNA 没有消失,另1例治疗失败。副作用包括发热、嗜睡和骨髓抑 Treatment of delta infection is controlled by antiviral drugs. Thomas treated 10 patients with delta-infected chronic active hepatitis or cirrhosis for 12 weeks three times a week for 10 weeks with 10 million units / m 2 of a-interferon-like lymphoblastoid cells. Three cases showed a complete response to the disappearance of δ RNA in the serum liver; one was partially reduced but HDV-RNA did not disappear and the other failed. Side effects include fever, lethargy and myelosuppression