家族性C蛋白缺乏患者具有正常视网膜血管结构

来源 :世界核心医学期刊文摘.眼科学分册 | 被引量 : 0次 | 上传用户:nqqlove
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PURPOSE: It is unclear whether protein C deficiency is associated with retinal venous occlusive disease. DESIGN: We performed a cross-sectional study. METHODS: Members of a protein C-deficient family, either deficient or nondeficient, with a history of nonocular venous thrombosis were included. All participants completed questionnaires regarding their medical and ophthalmic histories. Each subject underwent dilated direct ophthalmoscopic and binocular indirect ophthalmoscopic examinations by a single vitreoretinal specialist. RESULTS: None of the 18 family members with a known history of nonocular thrombosis-12 with and 6 without protein C deficiency-manifested stigmas of recent or chronic retinal vascular occlusive disease. CONCLUSIONS: This study showed no evidence of involvement of the retinal vascular bed in a family with an increased risk of nonocular venous thrombosis attributable to the deficiency of protein C. PURPOSE: It is unclear whether protein C deficiency is associated with retinal venous occlusive disease. METHODS: Members of a protein C-deficient family, either deficient or nondeficient, with a history of nonocular venous thrombosis All participants completed questionnaires regarding their medical and ophthalmic histories. Each subject underwent dilated direct ophthalmoscopic and binocular indirect ophthalmoscopic examinations by a single vitreoretinal specialist. RESULTS: None of the 18 family members with a known history of nonocular thrombosis-12 with and 6 without protein C deficiency-manifested stigmas of recent or chronic retinal vascular occlusive disease. CONCLUSIONS: This study showed no evidence of involvement of the retinal vascular bed in a family with an increased risk of nonocular venous thrombosis attributable to the deficiency of protein C.
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