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目的分析1例紫杉醇注射液致心肌损害的药物不良反应。方法用回顾性分析方法,收集该例药物不良反应(ADR)的相关临床信息,对其发生原因进行探讨。结果与结论紫杉醇注射液导致的心脏毒性可在化疗后一段时间甚至数年后才表现出来,医师及药师应予以重视;同时做好药物不良反应监测工作,为其说明书修订提供参考。
Objective To analyze the side effects of paclitaxel injection on myocardial damage. Methods The retrospective analysis was used to collect the relevant clinical information of adverse drug reaction (ADR) in this case and to discuss its causes. RESULTS AND CONCLUSION: Cardiotoxicity caused by paclitaxel injection can be demonstrated only after a period of chemotherapy or even several years after chemotherapy. Physicians and pharmacists should pay attention to it. At the same time, monitoring of ADRs should be done to provide reference for the revision of the instructions.