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目的观察低温环境下放射性与火器复合伤(下称放火器复合伤)后伤道及血液细菌学变化特点,为其临床救治提供理论依据。方法以30只新西兰大白兔制备低温放火器复合伤动物模型,分别于致伤后0、4、8、16、24、48 h进行实验动物体温变化动态观察,伤道及血液中的细菌定性培养及菌群种类分析。结果低温放火器复合伤动物体温伤后明显升高,伤后4 h平均体温达(39.47±0.39)℃,体温变化趋势非常显著。伤后4 h,伤道局部分泌物中细菌为表面菌群,伤后8 h检测到肠道菌群。血液中出现细菌的时间为伤后8 h,既有表面菌群,又有肠道菌群。结论低温放火器复合伤后体温升高明显,细菌感染较严重,细菌入血时间早,肠道细菌容易入血,处理应尽早清创,早期合理使用广谱抗生素。
Objective To observe the characteristics of bacteriological changes of injured wounds and blood after radiation and firearm complex injury (hereinafter referred to as “firearm compound injury”) in low temperature environment, and provide a theoretical basis for its clinical treatment. Methods Thirty New Zealand white rabbits were used to prepare animal model of combined injury of low temperature arrester. Dynamic changes of body temperature were observed at 0, 4, 8, 16, 24 and 48 h after injury respectively. Specimens of wounds and blood were qualitatively cultured And flora analysis. Results Compared with the control group, the temperature of injured body increased significantly after warm injury. The average body temperature reached 39.47 ± 0.39 ℃ 4 h after injury, and the change trend of body temperature was very significant. At 4 h after injury, the bacteria in the local secretions of the injured wounds were surface micro-flora, and intestinal micro-flora was detected at 8 h after injury. Bacteria appeared in the blood 8 hours after injury, both the surface flora, but also intestinal flora. Conclusion The body temperature increased obviously after combined injury of low-temperature firearm. The bacterial infection was more serious. The bacteria were infiltrated into the bloodstream earlier. The intestinal bacteria were easy to enter the bloodstream. The treatment should be debridement as soon as possible, and the broad-spectrum antibiotics should be used rationally in the early stage.