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目的:探讨老年冠心病心衰患者在常规治疗基础上,通过应用曲美他嗪后对左室功能的影响。方法:曲美他嗪组在给予常规治疗基础上加用曲美他嗪治疗;常规治疗组仅进行常规治疗方法。结果:曲美他嗪组患者在治疗后总有效率为75.6%,明显高于常规治疗组的总有效率57.6%,且曲美他嗪组治疗后LVEF、SV也较治疗前以及常规组治疗后有显著提高。结论:曲美他嗪在治疗老年冠心病心衰发面发挥了基于线粒体能量代谢的心肌保护作用,临床上他们比单纯的基础药物治疗更进一步改善了心功能,提高老年病人的生存质量,非常值得临床上推广。
Objective: To investigate the effect of trimetazidine on left ventricular function in elderly patients with heart failure and coronary heart disease based on routine treatment. Methods: The trimetazidine group was treated with trimetazidine based on the conventional treatment, while the conventional treatment group was only given routine treatment. Results: The total effective rate of trimetazidine group after treatment was 75.6%, which was significantly higher than that of conventional treatment group (57.6%). LVEF and SV of trimetazidine group were also higher than those before and after treatment After a significant increase. Conclusion: Trimetazidine plays a cardioprotective role based on mitochondrial energy metabolism in the treatment of elderly patients with CHD. In clinical practice, trimetazidine further improves heart function and improves the quality of life of elderly patients compared with simple basic drug treatment Worth clinical promotion.