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目的：观察脱品司琼（ｔｒｏｐｉｓｅｔｒｏｎ）治疗肝癌经皮肝动脉化学疗法（化疗）栓塞术（ＴＡＣＥ）后的胃肠道反应。方法：１７例接受ＴＡＣＥ治疗的肝脏肿瘤病人，随机分为２组，脱品司琼组９例（男性８例，女性１例，年龄５５±ｓ１１ａ），ＴＡＣＥ前１ｈ以脱品司琼５ｍｇ静脉滴注（静滴）；昂丹司琼组８例（男性７例，女性１例，年龄５８±８ａ），ＴＡＣＥ术中化疗灌注前１５ｍｉｎ用昂丹司琼８ｍｇ静脉推注，术后昂丹司琼８ｍｇ静滴。结果：脱品司琼对恶心、呕吐的有效控制率为７８％，与昂丹司琼比较疗效差别无显著意义。未观察到副作用。结论：脱品司琼与昂丹司琼对防止化学治疗引起的恶心与呕吐疗效相仿。
Objective: To observe the gastrointestinal reactions of tropisetron in the treatment of hepatocellular carcinoma after percutaneous transhepatic arterial chemoembolization (chemotherapy) embolization (TACE). Methods: Thirteen patients with hepatic tumors treated with TACE were randomly divided into two groups. There were 9 patients in the desipromycin group (8 males and 1 female, age 55±s11a). Instillation (intravenous); Ondansetron group 8 patients (7 males, 1 female, age 58 ± 8a), TACE intraoperative chemotherapy 15min before injection with ondansetron 8mg intravenous injection, postoperative An ondan Siqiong 8mg intravenously. RESULTS: The effective control rate of desipromycin on nausea and vomiting was 78%. There was no significant difference in efficacy between ondansetron and ondansetron. No side effects were observed. CONCLUSIONS: Trieptase and ondansetron have similar efficacy in preventing nausea and vomiting caused by chemotherapy.