免疫学用于妇科恶性肿瘤的诊治已有多年历史,早在1943年Gross首先报道动物肿瘤中有特异性抗原,此后许多学者探讨了免疫与妇科恶性肿瘤的关系。近年来卵巢上皮癌的单克隆及多克隆抗体,在临床试用中已显示出很高的特异性和敏感性。随着细胞生物学的发展以及放射免疫技术的广泛应用,用生物导弹对卵巢癌进行早期诊断、病情监测及免疫治疗,是目前癌瘤领域中的研究方向。 Immunology for the diagnosis and treatment of gynecologic malignancies has many years of history, as early as 1943 Gross first reported in animal tumors have specific antigens, many scholars since then explored the relationship between immunity and gynecologic malignancies. In recent years, monoclonal and polyclonal antibodies against epithelial ovarian cancer have shown high specificity and sensitivity in clinical trials. With the development of cell biology and the widespread application of radioimmunoassay, early detection, condition monitoring and immunotherapy of ovarian cancer with biological missiles are currently the research directions in the field of cancer.