原发性肾上腺皮质功能减退症(PHAC)分急性慢性两类。典型的急性PHAC多见于肾上腺出血或梗死引起的华佛氏综合征及双侧肾上腺全切除术后,病情危急,病死率甚高。慢性PHAC多见于爱迪森氏病,发病缓慢,但严重应激诱发PHAC时亦甚危急。兹着重介绍其替代疗法。一、急性PHAC。有两型。(一)急性全皮质功能低下型:患者既缺皮质醇又缺醛固酮。治疗原则是 Primary adrenocortical hypofunction (PHAC) divided into acute and chronic two categories. A typical acute PHAC more common in adrenal bleeding or infarction caused by Warburg’s syndrome and bilateral total adrenalectomy, the critical condition, high mortality. Chronic PHAC more common in Addison’s disease, the incidence is slow, but when serious stress induced PHAC is also very critical. It focuses on its alternative therapies. First, acute PHAC. There are two types. (A) of acute cortical hypofunction: patients both lack of cortisol and lack of aldosterone. The principle of treatment is