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目的观察和分析早期强化血压控制对60例高血压脑出血者血肿的干预效果,以期探索一种有效途径和方法降低致残率和死亡率、改善患者预后。方法选取2011年5月~2012年6月60例高血压脑出血者于早期强化血压控制(试验组),另外再于同期随机选取58例常规血压控制的高血压脑出血者作为对照Ⅰ组以及55例血压暂未控制的高血压脑出血者作为对照Ⅱ组分别进行对比观察和研究,且对三组高血压脑出血者血肿扩大情况、平均治疗时间和临床治疗效果以及生存质量进行观察和随访活动,同时对其所得数据结果予以统计学处理分析。结果试验组治疗总有效率(95.00%)高于对照Ⅰ组(81.03%)、对照Ⅱ组(60.00%),P<0.05;试验组血肿扩大率(5.00%)和24h后血肿体积均低于对照Ⅰ组、对照Ⅱ组,P<0.05,且平均治疗时间(20.00±3.00)d较对照Ⅰ组、对照Ⅱ组缩短,P<0.05;3个月后,试验组生存质量随访活动评分显示试验组优于对照Ⅰ组与对照Ⅱ,P<0.05。结论早期强化血压控制是干预高血压脑出血所致血肿扩大的有效途径之一,能有效降低致残率、死亡率、改善患者预后,值得临床根据患者情况推广使用。
Objective To observe and analyze the effect of early intensive blood pressure control on hematoma of 60 patients with hypertensive intracerebral hemorrhage in order to explore an effective way and method to reduce the morbidity and mortality and improve the prognosis of patients. Methods From May 2011 to June 2012, 60 cases of hypertensive intracerebral hemorrhage were treated with early intensive blood pressure control (experimental group). In addition, 58 cases of conventional hypertensive intracerebral hemorrhage with blood pressure control were randomly selected as control group Ⅰ and Fifty-five patients with hypertensive intracerebral hemorrhage temporarily under control of blood pressure were compared and studied as control group Ⅱ respectively. The hematoma enlargement, mean duration of treatment, clinical effect and quality of life of three hypertensive intracerebral hemorrhage were observed and followed up Activities, at the same time, the data obtained from the results of their statistical analysis. Results The total effective rate (95.00%) in the experimental group was significantly higher than that in the control group (81.03%) and control group (60.00%), P <0.05. The hematoma expansion rate in the experimental group (5.00% Control group Ⅱ, control group Ⅱ, P <0.05, and the average treatment time (20.00 ± 3.00) d was shorter than control group Ⅰ and control group Ⅱ, P <0.05; after 3 months, the quality of life of follow- Group than control group Ⅰ and control Ⅱ, P <0.05. Conclusions Early intensive blood pressure control is one of the effective ways to intervene the expansion of hematoma caused by hypertensive intracerebral hemorrhage. It can effectively reduce the morbidity and mortality and improve the prognosis of patients. It is worth to be popularized in clinic according to the patient’s condition.