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对78例卵巢恶性肿瘤患者和150例正常和病理对照进行血清唾液酸(SA)测定。并对部分卵巢癌患者在治疗过程中进行动态血清 SA 观察。结果提示卵巢癌患者血清 SA含量明显高于正常对照和卵巢良性肿瘤及妇科其它良性疾病。血清 SA 含量与病情的严重程度呈正比,与组织学类型无关。绝大多数病人术后血清 SA 含量下降。治疗有效时,SA 持续下降接近正常。治疗无效或复发时,血清 SA 水平相继升高。
Serum sialic acid (SA) was measured in 78 patients with ovarian cancer and 150 normal and pathologic controls. And some ovarian cancer patients in the course of treatment of dynamic serum SA observation. The results suggest that serum SA levels in patients with ovarian cancer were significantly higher than the normal control and benign ovarian tumors and other benign gynecological diseases. The content of serum SA is proportional to the severity of the disease and has nothing to do with histological type. The vast majority of patients with postoperative serum SA decreased. When treatment is effective, SA continued to decline close to normal. The treatment of ineffective or relapse, serum SA levels have increased.