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1986～1987年新疆南部和田发生了一起肠道传播的非甲非乙型肝炎的流行。本研究用免疫电镜方法(IEM)对6例急性期病人的60份粪便标本进行了排病毒规律的检测。其中5例排病毒阳性(83.3％);全部粪便标本的病毒颗粒检出率为28.3％(17/60)。发病前1～4天的粪便标本阳性率为100％(3/3);发病后9～12天的阳性率为14.3％(1/7);发病两周后的22份标本全部阴性。17份不同病期收集的阳性粪便标本,94.1％(16/17)出现在病人血清转氨酶(SGPT)高峰值前,此时SGPT在100IU/L以下。故此,肠道传播的非甲非乙型肝炎患者的隔离期,应定为病后2～3周。
Between 1986 and 1987, an intestinal transmission of non-A, non-B hepatitis occurred in southern Xinjiang. In this study, immunodetection electron microscopy (IEM) in six cases of acute phase of the 60 stool specimens were tested for the virus pattern. Among them, 5 were negative for virus (83.3%). The detection rate of virus particles in all stool samples was 28.3% (17/60). The positive rate of stool specimens was 100% (3/3) 1 to 4 days before onset; the positive rate was 14.3% (1/7) 9 to 12 days after onset; and all 22 specimens were negative after two weeks. Positive stool samples collected from 17 different stages showed 94.1% (16/17) of the patients before SGPT peak, at which SGPT was below 100 IU / L. Therefore, the gut non-A non-hepatitis B patients isolated period, should be defined as sick after 2 to 3 weeks.