癫痫是一临床常见综合征,为了探讨其发病原因,多年来在遗传、生理、生化等方面作了大量的研究工作。人们经历了由大体解剖到微观的电镜下超微结构,由头皮电极、皮层电极的电生理到分子水平的生化学研究。晚近免疫学的发展,为癫痫的病因学研究开辟了新领域。大量的临床资料表明,癫痫病人确实存在免疫功能紊乱。现就有关问题综述如下。 Epilepsy is a common clinical syndrome, in order to explore its causes, over the years in genetics, physiology, biochemistry and made a lot of research work. People have undergone an electron microscopic ultrastructure from gross anatomy to microscopic examination of the electrophysiological to molecular level of the scalp electrodes and cortical electrodes. The recent development of immunology, for the etiology of epilepsy has opened up new areas. A large number of clinical data show that epilepsy patients do exist immune dysfunction. The relevant issues are summarized below.