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目的研究老年患者阻塞性睡眠呼吸暂停综合征症状严重程度与周边动脉硬化以及老年高血压、糖尿病病症的关系。方法 112例阻塞性睡眠呼吸暂停综合征老年患者,其中包含轻度睡眠呼吸暂停综合征患者28例(A组);中度睡眠呼吸暂停综合征患者38例(B组);重度睡眠呼吸暂停综合征患者46例(C组),对患者进行颈动脉以及下肢股动脉超声检测,并对患者进行全天血压、血糖等指标的检查。结果 C组患者的24 h平均收缩压(140.4±9.4)mm Hg、夜间收缩压(139.6±13.5)mm Hg、糖化血红蛋白为(8.38±0.34)%、颈动脉不稳定斑块38例(82.61%);B组患者的24 h平均收缩压(139.4±12.9)mm Hg、夜间收缩压(129.3±12.4)mm Hg、糖化血红蛋白为(6.86±0.14)%、颈动脉不稳定斑块19例(50.00%);C组患者的24 h平均收缩压(130.7±8.8)mm Hg、夜间收缩压(123.4±10.7)mm Hg、糖化血红蛋白为(5.14±0.28)%、颈动脉不稳定斑块7例(25.00%);三组以上指标比较差异有统计学意义(P<0.05)。结论睡眠呼吸暂停综合征与动脉硬化、血压、血糖等数据呈正相关,严重的睡眠呼吸暂停综合征老年患者更容易发生高血压、2型糖尿病、颈动脉以及下肢动脉硬化等症状。
Objective To study the relationship between the severity of obstructive sleep apnea syndrome and peripheral arteriosclerosis and senile hypertension and diabetes mellitus in elderly patients. Methods A total of 112 elderly patients with obstructive sleep apnea syndrome, including 28 patients with mild sleep apnea syndrome (group A), 38 patients with moderate sleep apnea syndrome (group B), severe sleep apnea syndrome 46 patients were enrolled in the study (group C). The carotid arteries and femoral arteries of the lower extremities were examined by ultrasound and the patients were examined for blood pressure and blood glucose during the whole day. Results The average systolic pressure at 24 h (140.4 ± 9.4) mm Hg, nighttime systolic pressure (139.6 ± 13.5) mm Hg, glycosylated hemoglobin was (8.38 ± 0.34)% and carotid artery unstable plaque was 38 (82.61% ). The mean systolic blood pressure at 24 h (139.4 ± 12.9) mm Hg, nighttime systolic blood pressure (129.3 ± 12.4) mm Hg, glycated hemoglobin (6.86 ± 0.14)% and carotid artery plaque in 19 patients %). The mean systolic blood pressure (CSP), the average systolic pressure (C), the systolic blood pressure (C), the systolic blood pressure 25.00%). There were significant differences among the above three groups of indicators (P <0.05). Conclusion Sleep apnea syndrome is positively correlated with atherosclerosis, blood pressure, blood glucose and other data. Serious sleep apnea syndrome is more likely to occur in elderly patients with hypertension, type 2 diabetes mellitus, carotid artery and lower extremity arteriosclerosis.