目的:Petersen疝是胃癌胃切除术后少见但严重的并发症。但目前国内外对Petersen疝的报道十分有限。因此，本文总结胃癌胃切除术后Petersen疝的临床特征和治疗方式，为临床诊治提供参考。方法:本研究采用描述性病例系列研究方法。通过南京大学医学院附属鼓楼医院消化道肿瘤数据库，筛选自2010年1月至2019年12月期间收治的Petersen疝患者。病例纳入标准：经术中证实为Petersen疝；既往接受过胃癌切除术；临床资料完整。分析总结本组Petersen疝临床表现、围手术期情况及治疗后随访情况。结果:全组12例患者均为男性，年龄（65.3±8.5）岁，中位发病时长21（6~143）h，常见主诉包括腹痛和腹胀。所有患者均为急诊入院，术前CT均表现为小肠扩张积液，其他影像学表现包括漩涡征、靶征、肠系膜回缩或充血水肿、腹盆腔积液等。血液学检查显示患者白细胞计数、中性粒细胞比例、降钙素原及C反应蛋白均高于正常范围。距上次胃切除术20.5（0.5~55.0）个月，胃切除术式为腹腔镜手术2例，开放手术10例。10例即刻接受了急诊手术，2例经保守治疗无效后行手术治疗。6例经小肠复位后血供恢复未行小肠切除，另6例术中证实小肠坏死行部分小肠切除术，中位切除长度为76（11~300）cm。6例术后转入重症监护室，重症监护室住院天数为（2.5±0.8）d；1例因小肠广泛坏死行小肠次全切除术，术后2 d死亡；其他11例术后均未发生Clavien-Dindo分级Ⅲ级或以上并发症；全组患者术后总住院时间（9.2±3.6）d。术后随访，均未再出现急性消化道症状或急腹症。结论:胃癌术后Petersen疝发病急、进展快，多集中于男性，预后不良。“,”Objective:Petersen hernia is a rare but severe complication after gastrectomy, which has been reported by very few studies. This study is dedicated to summarize the clinical characteristics and management of Petersen hernia after gastrectomy in patients with gastric cancer in order to provide reference to clinical practice.Methods:A descriptive case-control study was carried out. All the qualified patients were screened from the database of digestive malignancies in Nanjing Drum Tower Hospital. The inclusion criteria were as follows: Petersen hernia confirmed during operation; previous gastrectomy history due to gastric cancer; complete clinical data. The clinical manifestation, perioperative data and follow-up outcome were summarized.Results:A total of 12 qualified patients were included. They were all male with a mean age of (65.3±8.5) years old, and whose clinical presentation had last for (6~143) hours (median: 21 hours). Common complaints included abdominal pain and bloating. All the patients were admitted to the emergency department. Preoperative CT showed dilatation and effusion of small intestine. Other imaging manifestations included whirlpool sign, target sign, mesenteric retraction or congestion and edema, abdominal and pelvic effusion, etc. Hematological examination showed white blood cell count, ratio of neutrophils, procalcitonin and C-reactive protein were higher than the normal range. The median interval to previous gastrectomy is 20.5 (0.5-55.0) months. The previous gastrectomy of 12 cases included 2 cases of laparoscopic surgery and 10 of laparotomies. Ten cases underwent emergency surgery immediately, and 2 cases underwent surgery after ineffective conservative treatment. Six cases received small bowel restoration without bowel resection, and the other 6 cases received small bowel resection with a mean length of 76 (11~300) cm. Six cases were transferred into ICU with a stay of (2.5±0.8) days. One case deceased at postoperative day 2, due to subtotal small bowel resection, and the other 11 cases survived without grade III or above complication according to Clavien-Dindo classification. The overall postoperative hospitalization was (9.2±3.6) days. During the postoperative follow-up, no acute gastrointestinal symptoms or acute abdomen recurred.Conclusions:Petersen hernia is more common in male, whose onset and progress are rapid and emergent, and prognosis is poor.