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目的：研究脑胶质细胞瘤中C－myc癌基因蛋白产物的表达。方法：利用SP免疫组织化学方法，检测66例脑胶质细胞瘤。结果：C－myc癌基因蛋白在脑胶质瘤中的表达率为37．88％，星形细胞瘤与室管膜瘤表达率之间，Ⅰ、Ⅱ级肿瘤与Ⅲ、Ⅳ级肿瘤表达率之间均无显著性差异（P＞0．05），但高强度表达的病例大部分见于Ⅲ、Ⅳ级肿瘤（6／9）。结论：脑肢质细胞瘤中存在C—myc癌基因蛋白产物的表达，其表达率与胶质瘤的组织学类型及分化程度无关，但表达量的多寡反映种瘤的恶性程度。
Objective: To study the expression of C-myc oncogene protein product in brain glioma. Methods: Sixty-six cases of brain glioma were detected by SP immunohistochemistry. Results: The expression rate of C-myc oncoprotein in glioma was 37.88%. The expression rate of astrocytoma and ependymoma, and the expression rate of grade I and II tumors and grade III and IV tumors. There was no significant difference between them (P>0.05), but high-intensity cases were mostly seen in grades III and IV (6/9). Conclusion: The expression of C-myc oncogene protein product is present in cerebral acromegaly. The expression rate is not related to the histological type and differentiation of glioma, but the amount of expression reflects the malignant degree of tumor.