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动脉粥样硬化的发生、发展过程中炎症反应起着关键作用，血浆正五聚蛋白－3作为新型的心血管炎性标志物在粥样硬化病变中大量产生，并且与心血管疾病密切相关，现就正五聚蛋白－3和心血管疾病关系的研究进展做一综述。“,”Inflammation has been recognized as the central mechanism underlying atherogenesis .Plasma pentraxin-3, as a novel in-flammation biomarker for cardiovascular disease , is expressed predominantly in atherosclerosis lesions and closely associated with cardiovas -cular disease .The paper reviews the relationship between pentraxin-3 and cardiovascular disease .