Objective: To compare the effects of 3 fluoride-containing agents on the remineralization of deciduous teeth in vitro. Methods: Thirty-six deciduous teeth were selected and divided into 4 groups randomly. The specially limited areas of each tooth was exposed and etched. Then etched teeth in group 1, 2 and 3 were treated with 10% (NH4)2MoO2F4solution, 38% Ag(NH3)2F solution and APF-LaCl3 solution for 3 min respectively. Group 4 served as control. After that,each tooth was put into a bottle containing 5 ml remineralization solutions. Four days later, the concentrations of Ca2+ ions in the remineralization solutions were measured. Then statistical analyses were performed on changes of Ca2+ ion amounts among the groups. Results: Compared with the control, the groups treated with fluoride-containing agents all showed significant reduction in Ca2+ion amounts in the remineralization solutions. Among the experimental groups, reduction of Ca2+ion amounts in groups treated with APF-LaC13 or 38% Ag(NH3)2F solution was more obvious than that of the group with 10% (NH4)2MoO2F4 solution treatment. But no difference in the reduction of Ca2+ ion amounts was found between the first 2 groups. Conclusion: All the 3 fluoride-containing agents can promote the remineralization ofdeciduous teeth in vitro,and both APF-LaCl3 and 38% Ag(NH3)2F solution are more effective on remineralization than 10% (NH4)2MoO2F4 solution while the former 2 differ insignificantly.