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目的探讨进展期(ⅡⅢa期)胃癌的手术方法及术后早期腹腔化疗的临床意义。方法对30例进展期胃癌进行回顾性分析,根冶性全胃切除13例(43.3%),姑息性全胃切除17例(56.6%),其中合并胰体尾切除3例(10.0%),消化道重建使用吻合器27例(90.0%),术后早期行表阿霉素、5-Fu腹腔化疗25例(83.3%)。结果手术死亡1例(3.3%),吻合口漏1例(3.3%),对28例(93.3%)进行术后随访,1、3、5年生存率分别为85.7%,46.4%和39.3%。结论选择合理术式及术后早期腹腔化疗,对延长患者生存期和提高生活质量具有重要的意义。
Objective To investigate the surgical methods of advanced stage (IIIIIa) gastric cancer and the clinical significance of early postoperative intraperitoneal chemotherapy. Methods Thirty cases of advanced gastric cancer were retrospectively analyzed. Thirty-three cases (43.3%) had total root gastrectomy, and 17 cases (56.6%) had palliative total gastrectomy. There were 3 cases with pancreatic body excision. 10.0%). In the digestive tract reconstruction, 27 patients (90.0%) were used as staplers, and 25 patients (83.3%) received intraperitoneal chemotherapy with epirubicin and 5-Fu. Results One patient died of surgery (3.3%), anastomotic leakage occurred in one patient (3.3%), and 28 cases (93.3%) were followed up. The 1-, 3-, and 5-year survival rates were 85.7%. , 46.4% and 39.3%. Conclusion Choosing reasonable operation and early postoperative intraperitoneal chemotherapy are important for prolonging the survival time and improving the quality of life.