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作者回顾性研究了２９２例老年腹部外科急症患者的全身性炎症反应综合征（ＳＩＲＳ）和多脏器功能不全综合征（ＭＯＤＳ）的临床资料，分析ＳＩＲＳ向ＭＯＤＳ的发展过程，探索ＭＯＤＳ的防治策略。结果：老年腹部外科急症患者入院时ＳＩＲＳ的发生率是４１．１％，其后ＭＯＤＳ的发生率是１４．２％，病死率是１１．７％。经治疗４８小时后（包括手术和保守治疗），仍伴有ＳＩＲＳ的病例中，４０．５％（１７／４２）发展为ＭＯＤＳ。２９２例老年腹部外科急症患者中，１９例发生ＭＯＤＳ（６．５％），１６例死亡（８４．２％），结论：早期诊断ＳＩＲＳ，特别注意分析治疗４８小时后仍伴有ＳＩＲＳ的患者的原因，积极调控机体炎症反应，才是改善老年腹部外科急症患者预后的关键
The authors retrospectively studied the clinical data of 292 elderly patients with acute abdominal surgery who had systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS), analyzed the development of SIRS to MODS, and explored the strategies for the prevention and treatment of MODS . Results: The incidence of SIRS in hospitalized elderly patients with abdominal surgery was 41.1%, followed by MODS incidence 14.2% and mortality 11.7%. Forty-five hours after treatment (including surgery and conservative treatment), 40.5% (17/42) of the cases with SIRS still developed MODS. Among 292 elderly patients with abdominal surgery emergency, MODS (6.5%) and 16 deaths (84.2%) occurred in 19 patients. CONCLUSIONS: SIRS were diagnosed early, with special attention being given to the analysis of patients who were still associated with SIRS 48 hours after treatment The reason, and actively regulate the body’s inflammatory response, is the key to improve the prognosis of elderly patients with abdominal surgery emergency