皮肌炎是一种累及肌肉和皮肤的自身免疫性结缔组织病。皮肌炎主要特征是受累肌群的肌无力、疼痛,特异性皮肤表现,伴发热、自身抗体阳性等[1]。钙沉着症在皮肌炎患者中,多见于儿童[2],在成人发生率低,而同时出现间质性肺炎则较罕见,也是死亡的主要原因。现报道1例59岁女性皮肌炎患者,同时合并间质性肺炎与四肢皮下、肌肉广泛钙质沉着 Dermatomyositis is an autoimmune connective tissue disease involving the muscles and the skin. Dermatomyositis is mainly characterized by muscle weakness, pain, specific skin manifestations, with fever, autoantibodies and other positive [1]. Calcytosis is more common in children with dermatomyositis, 2 with a lower incidence in adults and more common with interstitial pneumonia and the leading cause of death. Is reported in a 59-year-old female dermatomyositis patients, combined with interstitial pneumonia and limbs subcutaneous, extensive muscle calcification