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目的:观察痰热清注射液佐治儿童手足口病的疗效。方法:将218例手足口病Ⅰ期患儿随机分为治疗组112例和对照组106例,两组均采取抗病毒(利巴韦林)、营养支持(水溶性维生素)等常规治疗,治疗组加用痰热清注射液0.4～0.6 mL/(kg.d),治疗3 d后观察两组患儿发热、皮疹等症状改善情况及临床疗效。结果:治疗组总有效率为88.4%,对照组为72.6%,两组比较差异有统计学意义(χ2=5.67,P<0.01);治疗组退热时间和皮疹消退时间分别为(1.43±0.07)d、(2.45±0.74)d,对照组分别为(3.04±1.08)d、(3.33±1.06)d,两组比较差异有统计学意义(P<0.05、P<0.01);治疗过程中两组均未发现明显不良反应。结论:痰热清注射液佐治儿童手足口病具有明显的退热、退疹作用,且安全性好。
Objective: To observe the effect of Tanreqing injection on children with hand-foot-mouth disease. Methods: One hundred and eighty-eight cases of HFMD Ⅰ were randomly divided into treatment group (112 cases) and control group (106 cases). Both groups were treated with anti-virus (ribavirin) and nutritional support (water-soluble vitamins) Group plus Tanreqing injection 0.4 ~ 0.6 mL / (kg.d), after 3 days of treatment were observed in children with fever, rash and other symptoms and improvement of clinical efficacy. Results: The total effective rate was 88.4% in the treatment group and 72.6% in the control group, the difference between the two groups was statistically significant (χ2 = 5.67, P <0.01); the treatment group was 1.43 ± 0.07 ), d (2.45 ± 0.74) d respectively, and the control group was (3.04 ± 1.08) d and (3.33 ± 1.06) d respectively. The difference between the two groups was statistically significant (P <0.05, P <0.01) No significant adverse reactions were found in the group. Conclusion: Tanreqing injection of children with hand-foot-mouth disease with fever, fever, rash, and good safety.