恒速iv乌头碱7.48mg/L·min~(-1)可引起小鼠多种心律失常。牛磺酸100mg/kg iv或奎尼丁5mg/kg iv分别可使心律失常发生时间推迟,乌头碱用量增加,与对照组比较有显著差别。牛磺酸50mg/kg iv或奎尼丁2.5mg/kg vi不能对抗乌头碱引起的心律失常,如两药合用,则可降低室颤的发生率,死亡时间亦推迟。实验提示:牛磺酸、奎尼丁及两药联合应用,有较好抗乌头碱心律失常作用。 Constant speed iv aconitine 7.48mg / L · min ~ (-1) can cause a variety of arrhythmias in mice. Taurine 100mg / kg iv or quinidine 5mg / kg iv can delay the onset of arrhythmia, aconitine dosage increased compared with the control group were significantly different. Taurine 50mg / kg iv or quinidine 2.5mg / kg vi can not fight aconitine-induced arrhythmias, such as the two drugs combined, can reduce the incidence of ventricular fibrillation, the death was delayed. Experimental Tip: Taurine, quinidine and the two drugs combined with better anti-aconitine arrhythmia.