遗传性球形细胞增多症(简称HS)是一种常染色体显性遗传病。脾切除术对HS的疗效已被公认。我们应用脾切除术治疗2例取得效果。现报告如下: 病例报告 例1:薛×,14岁,男,汉族,因反复鼻出血,左上腹肿块10年余入院。否认黄疸病史,无服食药物,新鲜蚕豆不适史,无血尿或血红蛋白尿史。外祖母有贫血病史,父母体健,其姐有类似病史。体检:贫血貌,巩膜无黄染,皮肤无出血点。肝未扪及,脾左锁中线肋缘下6cm,肋缘至脾远端9cm,脾右缘至正中线一2cm、质中等、表面光滑,有轻度压痛。四 Hereditary spherocytosis (HS) is an autosomal dominant disease. The efficacy of splenectomy on HS has been recognized. We applied splenectomy in 2 cases to obtain results. Now report as follows: Case Report 1: XUE, 14 years old, male, Han, due to repeated epistaxis, left upper abdominal mass more than 10 years admitted to the hospital. Denied the history of jaundice, no medication, no history of fresh broad beans, no history of hematuria or hemoglobin. My grandmother has a history of anemia, parents healthy, her sister has a similar history. Physical examination: anemia appearance, sclera no yellow dye, no bleeding skin. Hepatic palpable, left spleen left midline rib margin 6cm, rib margin to spleen distal 9cm, right spleen to midline a 2cm, medium quality, smooth surface, mild tenderness. four