论文部分内容阅读
目的:通过监测血清降钙素原(PCT)变化及平均机械通气时间和住重症加强护理病房(ICU)时间探讨连续肾脏替代疗法(CRRT)集束化治疗感染性休克的疗效。方法:抽取中山市港口医院在2016年1月至2016年12月诊治的感染性休克患者56例,按照随机分组法,将患者分为观察组和对照组结果,观察组患者采用CRRT集束化治疗方法,对照组采用常规治疗未行CRRT治疗方法。比较两组患者在经过治疗后48 h后血浆中的PCT含量,比较两组患者的机械通气时间和住ICU时间,判断治疗有效率。结果:观察组的治疗有效率82.14%高于对照组患者的67.85%,差异具有统计学意义(P<0.05)。观察组的平均机械通气时间和住ICU时间均短于对照组,差异具有统计学意义(P<0.05)。结论:CRRT集束化治疗在临床治疗感染性休克上具有良好效果,能够使病人的生化指标及生命指标得到明显改善,使病死率降低,减少住ICU时间。
OBJECTIVE: To evaluate the efficacy of continuous renal replacement therapy (CRRT) in the treatment of septic shock by monitoring changes of serum procalcitonin (PCT), mean duration of mechanical ventilation, and duration of intensive care unit intensive care (ICU). Methods: Fifty-six patients with septic shock diagnosed and treated in Zhongshan Port Hospital from January 2016 to December 2016 were randomly divided into observation group and control group. The observation group was treated with CRRT cluster therapy Methods, the control group without conventional treatment of CRRT treatment. The plasma levels of PCT in the two groups were compared 48h after treatment, and the mechanical ventilation time and ICU time were compared between the two groups to determine the treatment efficiency. Results: The effective rate of observation group was 82.14% higher than that of the control group (67.85%), the difference was statistically significant (P <0.05). The mean duration of mechanical ventilation and ICU stay in the observation group were shorter than those in the control group, with statistical significance (P <0.05). CONCLUSION: The CRRT cluster therapy has a good effect in the treatment of septic shock in clinical practice, which can significantly improve the biochemical and life indices of patients and reduce the mortality rate and ICU time.