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目的:研究补肾活血方对氢化可的松致肾阴虚小鼠免疫功能的影响。方法:用氢化可的松制作小鼠肾阴虚模型,观察补肾活血方对T淋巴细胞染色率、吞噬碳粒、溶血素生成和迟发型超敏反应(DTH)的影响。结果:补肾活血方呈剂量依赖性增加肾阴虚小鼠的T淋巴细胞染色率、增加碳粒廓清指数、增强溶血素抗体生成及增强迟发型超敏反应(DTH)。结论:补肾活血方具有增强免疫功能和滋阴补肾的作用。
Objective: To study the effect of Bushen Huoxue Fang on immune function in mice with kidney yin deficiency caused by hydrocortisone. Methods: Hydroxycortisone was used to make mouse kidney yin deficiency model, and the effect of Bushen Huoxue Fang on T lymphocyte staining rate, phagocytic carbon particles, hemolysin production and delayed type hypersensitivity (DTH) was observed. RESULTS: Bushen Huoxue Decoction dose-dependently increased the staining rate of T lymphocytes, increased carbon particle clearance index, enhanced hemolysin antibody production, and enhanced delayed type hypersensitivity reaction (DTH) in mice with kidney yin deficiency. Conclusion: Bushen Huoxue Decoction has the function of enhancing immune function and nourishing yin and tonifying kidney.