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报告分别于1991年7月、1993年9月诊治Gardner综合征一家两例,均行全结肠切除、回直肠吻合术治愈,随访至今无异常发现。结合文献,对本病的诊断、鉴别诊断、治疗进行了讨论。Gardner综合征是结肠、直肠内多发腺瘤性息肉,并伴结肠外病变的常染色体遗传性疾病,是一种癌前病变;全结肠切除、回结肠吻合求是一种理论上合理、实践中可行、患者可接受的治疗方法。
In July 1991 and September 1993, two cases of Gardner syndrome were diagnosed and treated respectively. All patients underwent total colectomy and rectal anastomosis. No abnormalities were found since follow-up. Combined with the literature, the diagnosis, differential diagnosis and treatment of this disease were discussed. Gardner syndrome is an autosomal hereditary disease with multiple adenomatous polyps in the colon and rectum and associated with extracolonic lesions. It is a precancerous lesion; the total colectomy and ileoclastic anastomosis are theoretically reasonable and practical. Feasible, patient-acceptable treatment.