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目的:探讨药师参与临床治疗对呼吸内科住院患者抗生素合理应用的干预效果。方法:随机选择2014年4月~2016年4月期间住院治疗且使用抗生素的2252例患者作为研究对象,采用随机数字抽取表法将患者分为对照组和观察组,每组各1126例,其中给予对照组患者实施常规抗生素应用措施,给予观察组患者派驻临床药师参与抗生素应用措施,对两组患者抗生素使用强度、合理性及不良反应进行比较。结果:观察组患者使用强度低于对照组,使用合理率高于对照组,数据比较差异具有统计学意义(P<0.05);观察组患者不良反应发生率为2.75%,对照组患者不良反应发生率为15.89%,数据比较差异具有统计学意义(P<0.05)。结论:对呼吸内科住院患者采用药师参与临床治疗,能够进一步保证抗生素应用的合理性,降低不良反应发生率,具有重要的应用价值。
Objective: To investigate pharmacists participating in clinical treatment of respiratory patients inpatient antibiotics rational use of intervention. Methods: Totally 2252 patients admitted to hospital from April 2014 to April 2016 were enrolled in this study. The patients were divided into control group and observation group by random number extraction table method, with 1126 cases in each group The patients in the control group were given routine antibiotics and the clinical pharmacists were assigned to participate in the antibiotics in the observation group. The strength, rationality and adverse reactions of antibiotics in the two groups were compared. Results: The use intensity of the observation group was lower than that of the control group, the rational use rate was higher than that of the control group, the difference was statistically significant (P <0.05); the incidence of adverse reactions in the observation group was 2.75%, and the adverse reactions in the control group The rate was 15.89%, the difference was statistically significant (P <0.05). Conclusion: It is of great value to use pharmacists to participate in clinical treatment of inpatients in respiratory medicine, which can further ensure the rationality of antibiotic application and reduce the incidence of adverse reactions.