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目的:探讨尼莫地平治疗脑出血后缺血性脑损伤的临床效果。方法:选取我院于2012年6月-2014年6月神经科收治的脑出血患者80例,随机将其分为对照组和观察组,每组各40例。对照组行常规治疗,观察组在常规治疗基础上联合尼莫地平行静脉滴注,观察对比两组患者治疗前后神经功能缺损评分、临床治疗效果及不良反应发生率。结果:观察组患者经尼莫地平治疗后神经功能缺损评分及临床治疗效果均明显优于对照组患者,不良反应发生率也低于对照组,差异均具有统计学意义,(P<0.05)。结论:临床中治疗脑出血患者时,在常规治疗基础上再联合应用尼莫地平能有效减轻患者的缺血性脑损伤的程度,取得满意的临床治疗效果,值得推广应用。
Objective: To investigate the clinical effect of nimodipine in treating ischemic brain injury after intracerebral hemorrhage. Methods: Eighty patients with cerebral hemorrhage admitted in our hospital from June 2012 to June 2014 were randomly divided into control group and observation group, 40 cases in each group. The control group was treated routinely, and the observation group was given routine nimodipine combined with nimodipine intravenous drip. The scores of neurological deficits, clinical curative effect and incidence of adverse reactions were compared between the two groups before and after treatment. Results: The scores of neurological deficits and clinical effects after treatment with nimodipine in the observation group were significantly better than those in the control group. The incidence of adverse reactions was also lower in the observation group than in the control group. The differences were statistically significant (P <0.05). Conclusion: In the clinical treatment of patients with intracerebral hemorrhage, combined with nimodipine on the basis of routine treatment can effectively reduce the degree of ischemic brain injury in patients with satisfactory clinical results, which is worth popularizing and applying.