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目的:观察乳突根治术后,应用引导组织胶原膜对乳突腔愈合的影响。方法:41例胆脂瘤中耳炎患者行开放式乳突根治术,其中22例应用胶原膜加游离薄皮片(应用组)处理乳突术腔;19例只用游离皮片(未应用组)。术后随访,对比观察术腔愈合情况和上皮化时间。结果:应用组肉芽生长少,无复发,术腔上皮化时间为3~7周,平均(4.5±0.7)周;未应用组肉芽生长多,复发1例,术腔上皮化时间为5~12周,平均(7.2±0.8)周。对2组术腔上皮化时间行统计学检验,差异有统计学意义(P<0.01)。结论:医用胶原膜可促进上皮组织再生,减少术后感染及肉芽发生,加速乳突腔上皮化,提高乳突根治术疗效。
Objective: To observe the effect of guiding tissue collagen membrane on mastoid cavity healing after radical mastectomy. Methods: Forty-one patients with cholesteatoma otitis media underwent radical mastoidectomy. Twenty-two patients underwent mastoid cavity with collagen membrane and free thin-skinned tablets (application group). The patients were followed up and compared with the healing of the surgical cavity and the time of epithelialization. Results: The granulation tissue in the application group had less growth and no recurrence. The time of peritoneal epithelialization was 3 to 7 weeks with an average of (4.5 ± 0.7) weeks. Granulation did not occur in the application group, with 1 case of recurrence and 5 to 12 Weeks, an average of (7.2 ± 0.8) weeks. There was statistically significant difference between the two groups (P <0.01). Conclusion: Medical collagen membrane can promote epithelial tissue regeneration, reduce postoperative infection and granulation, accelerate mastoid cavity epithelialization and improve the efficacy of radical mastoidectomy.