新近有肌细胞脂质聚积的病理资料表明,脂质代谢障碍性肌病为一多源性发病机理的疾病.Angelini将这组疾病分为四个主要类型.一、与肉毒碱缺乏有关的Ⅰ型脂质沉积病肉毒碱缺乏的可能原因有肉毒碱合成缺乏、向细胞外液转换障碍、在组织中排出和破坏过多或假定的组织旦白受体缺乏.多在儿童或少年期起病,肢体近端进行性肌无力,预后相对良好.但Comelio报导 Recent pathologic data on myocyte lipid accumulation indicate that dyslipidemia is a multisource-specific disease that Angelini classifies into four major groups. One is related to the lack of carnitine Type I lipid deposition disease Carnitine deficiency may be due to the lack of synthesis of carnitine, to the extracellular fluid conversion disorders, excessive tissue destruction and discharge or hypothetical lack of tissue protein receptor more than in children or adolescents Period onset, proximal muscular weakness, the prognosis is relatively good, but Comelio reports