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心输出量是衡量心功能的重要指标,对循环系统疾病研究具有重要意义。国外对家兔心输出量(CO)正常值的报道,因方法各异而波动范围较大;国内尚未见报道。本实验用染料稀释法(dye dilution)测定家兔正常CO,同时记录平均动脉压(MABP)、心率(HR),以计算其衍生指标:心指数(CI)、每搏容量(SV)、左室每搏功(LVSW)、总外周阻力(TPR)。还观察了环境温度、禁食开腹、低血压状态等因素对上述指标的影响。
Cardiac output is an important measure of cardiac function, the study of circulatory diseases is of great significance. Foreign reports of normal rabbit cardiac output (CO), due to different methods and a larger range of fluctuations; has not been reported in China. In this experiment, the normal CO of rabbits was determined by dye dilution and mean arterial pressure (MABP) and heart rate (HR) were recorded at the same time to calculate the derivation indexes of heart index (CI), stroke volume (SV) Room stroke pound work (LVSW), total peripheral resistance (TPR). Also observed the environmental temperature, fasting fasting, hypotension and other factors on the above indicators.