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应用原位末端标记法（ＴＵＮＥＬ）和免疫组化技术对５０例卵巢癌术后石蜡包埋组织切片进行检测发现，卵巢癌组织中有细胞凋亡和ＢｃＬ－２蛋白的表达，二者阳性率分别为６８．００％（３４／５０）和５０．００％（２５／５０）。ＢｃＬ－２蛋白表达与细胞凋亡呈负相关。提示ＢｃＬ－２蛋白可能通过抑制细胞凋亡而参与卵巢癌的发生与发展。
TUNEL and immunohistochemistry were used to detect paraffin-embedded tissue sections of 50 cases of ovarian cancer. The results showed that there were apoptosis and BcL-2 protein expression in ovarian cancer tissues. They were 68.00% (34/50) and 50.00% (25/50), respectively. The expression of BcL-2 protein was negatively correlated with apoptosis. It suggests that BcL-2 protein may participate in the occurrence and development of ovarian cancer by inhibiting apoptosis.