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羊水栓塞(Amniotic fluid embolism,AFE)指的是由于羊水及羊水的有形成分在分娩过程中进入母体血液循环而导致产妇过敏性休克、急性肺栓塞、肾功能衰竭、血管内凝血甚至出现猝死一系列严重临床症状的综合症。本文从AFE的病理变化、病因、高危因素以及发病机制与IL-6,IL-8关系四个方面对AFE作简要综述,旨在提高羊水栓塞临床诊断与治疗水平,降低孕产妇死亡率。
Amniotic fluid embolism (AFE) refers to the sudden onset of death due to anaphylactic shock, acute pulmonary embolism, renal failure, intravascular coagulation due to the physical components of amniotic fluid and amniotic fluid entering the maternal blood circulation during childbirth Series of symptoms of severe clinical syndrome. This article reviews the AFE pathological changes, etiology, risk factors and the relationship between pathogenesis and IL-6, IL-8 in order to improve the clinical diagnosis and treatment of amniotic fluid embolism and reduce the maternal mortality rate.