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目的 探讨深圳市一般人群中输血传播病毒 (TTV)感染情况及其影响因素。方法采用多阶段随机抽样抽取研究对象 ,并用套式聚合酶链反应法 (nPCR)检测该人群血清中TTVDNA。结果 深圳市一般人群中TTVDNA总阳性率为 11.86% ,男女阳性率分别为 14 .67%和9.41% ;年龄组间TTVDNA阳性率差异无显著性 ,单因素和logistic回归分析未显示肝病史、近期手术史、注射史、拔牙史及乙型肝炎疫苗接种等因素与TTVDNA感染有关 ;HBsAg、抗 -HBs和抗 -HBc与TTV感染无统计学意义。但不同职业人群TTVDNA阳性率差异有显著性 ,地税干部和中小学教师TTVDNA阳性率高于其他人群。结论 深圳市一般人群中TTV感染率较高 ,尤其是地税干部和中小学教师 ,但其流行因素尚需进一步研究
Objective To investigate the prevalence of transfusion transmitted virus (TTV) in the general population in Shenzhen and its influencing factors. Methods The subjects were drawn by multistage random sampling and the serum levels of TTVDNA were detected by nested polymerase chain reaction (nPCR). Results The positive rate of TTVDNA in the general population in Shenzhen was 11.86%, the positive rates of male and female were 14.67% and 9.41% respectively. There was no significant difference in the positive rate of TTVDNA between the age groups. The univariate and logistic regression analysis showed no history of liver disease, The history of surgery, injection history, history of tooth extraction and hepatitis B vaccination and other factors related to TTVDNA infection; HBsAg, anti-HBs and anti-HBc and TTV infection was not statistically significant. However, there was a significant difference in the positive rate of TTVDNA between different occupational groups. The positive rate of TTVDNA among cadres in land tax and primary and secondary schools was higher than that in other populations. Conclusion The prevalence of TTV in the general population in Shenzhen is high, especially for cadres in land tax and primary and secondary schools, but the epidemic factors need further study