扑热息痛导致暴发性肝衰竭的病死率较高。哪些因素与预后有关,许多作者已从不同的角度进行了探讨,但单一凝血因子的检查尚未广泛开展。为此,作者对150例由扑热息痛引起的暴发性肝衰竭患者连续测定了凝血酶原时间(PT),以评价PT的变化和峰值时间对扑热息痛引起暴发性肝衰竭的预后价值。 1986年10月～1989年2月收治150例由扑热息痛诱发的暴发性肝衰竭。全部病例符 Paracetamol causes a higher case fatality rate for fulminant hepatic failure. What factors are associated with the prognosis, many authors have discussed from different angles, but the examination of single coagulation factor has not yet been widely carried out. To this end, the authors consecutively measured prothrombin time (PT) in 150 patients with fulminant hepatic failure caused by paracetamol to assess the prognostic value of PT changes and peak time on paracetamol-induced fulminant hepatic failure. From October 1986 to February 1989, 150 patients with fulminant hepatic failure induced by paracetamol were admitted. All cases of symbols