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目的:分析应用89SrCl高度亲骨性核素结合博宁治疗多发性骨转移癌骨痛的疗效。方法:对30例转移性骨癌疼痛患者,采用89SrCl结合博宁的方法进行治疗;结果:疼痛完全缓解15例,部分缓解13例,无效2例,总有效率93.3%。多数患者在给药后一周至10天逐渐起效,止痛时间持续4周以上。治疗后全身状况kamofsky评分提高到63.2分,与治疗前比较P<0.01,有显著差异。结论:89SrCl高度亲骨性核素结合博宁是治疗转移性骨癌较为有效的和可行的方法。
OBJECTIVE: To analyze the curative effect of 89SrCl highly osteophilic nuclide combined with Bonin in the treatment of multiple bone metastases and bone pain. Methods: Thirty patients with metastatic bone cancer were treated with 89SrCl combined with Boning. Results: 15 cases were relieved of pain, 13 cases were partially relieved and 2 cases were ineffective. The total effective rate was 93.3%. Most patients in the administration of a week to 10 days gradually onset, analgesic duration of 4 weeks or more. After treatment, the kamofsky score increased to 63.2, which was significantly different from that before treatment (P <0.01). CONCLUSIONS: 89SrCl highly osteophilic nuclide combined with Bonin is an effective and feasible method for the treatment of metastatic bone cancer.