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胰胆管末端、共同通道及十二指肠乳头均有不同厚度的平滑肌环绕,即胆道口括约肌(sphincter of Oddi,SO),此段长4 mm~6 mm.如 SO 不能正常地舒张,胆汁或(和)胰液引流不畅,导致胆汁瘀积或(和)胰腺炎,表现为反复发作的上腹痛、黄疸、淀粉酶升高等,谓之 SO 功能失调(SOD).一般将 SOD 分为狭窄性和功能性,前者包括纤维化、肥大、慢性乳头炎或腺肌炎;后者包括 SO 运动过速、收缩期基础压升高、逆向收缩过多、SO 对 CCK 的反常反应.临床上 SOD 可分为3型:SOD-Ⅰ型:多为器质性狭窄,表现为典型的胆源性绞痛、肝酶(ALP,γ-GT)
The end of the pancreaticobiliary duct, the common passage, and the duodenal papillae all have different thicknesses of smooth muscle, sphincter of Oddi (SO), which is 4 mm to 6 mm in length.Such as SO does not relax normally, bile or (And) poor drainage of pancreatic juice, leading to cholestasis or (and) pancreatitis, manifested as recurrent upper abdominal pain, jaundice, amylase increased, so-called SO dysfunction (SOD) And functional, the former include fibrosis, hypertrophy, chronic papillitis or adenomyosis; the latter including SO over-speed, systolic basal pressure, reverse contractions, SO abnormal response to CCK.Clinical SOD Divided into 3 types: SOD-Ⅰ type: mostly organic stenosis, manifested as typical biliary angina, liver enzymes (ALP, γ-GT)