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丙二醛(MDA)是一种三碳二醛,是脂质过氧化的结果,据报道MDA对细菌和哺乳动物细胞具弱致突变作用且对粘膜是一种肿瘤起动因子。Bond等报告19名置CuIUD妇女中8例宫颈粘液中能测到MDA,而21例置不含铜的IUD妇女的宫颈粘液中未测到MDA,CuIUD是当前世界上广为应用的最有效的IUD,作者在本文中报告了用特异的、敏感的离子对高效液相法对置CuIUD、置塑料IUD和未置IUD的正常妇女宫颈粘液中MDA含量测定的结果。研究包括23名健康妇女,其中9例22～36岁(平均30.3岁),未用IUD或激素避孕药作为对照,10例27～42岁(平均32.9岁)置Cu-7IUD,4例置
Malondialdehyde (MDA) is a three-carbon dialdehyde that is a result of lipid peroxidation. It has been reported that MDA has a weak mutagenic effect on bacterial and mammalian cells and is a tumor promoter to the mucosa. Bond et al. Reported that MDA was detected in 8 cervical mucus of 19 women with CuIUD and 21 women without Cu in their cervical mucus. CuIUD was the most widely used in the world at present IUD, the authors report the results of a determination of MDA in cervical mucus of normal women with specific, sensitive ion-pair high performance liquid phase contrast CuIUD, plastic IUD, and no IUD. The study included 23 healthy women, 9 of whom were 22 to 36 years old (mean, 30.3 years) without IUD or hormonal contraception as control and 10 27-42 years (mean 32.9 years) with Cu-7 IUD. Four patients