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目的:探讨开塞露灌肠在救治急性有机磷农药中毒患者的临床效果。方法:将2010年4～12月89例口服有机磷农药患者设为对照组1,采用常规处理,即洗胃加20%甘露醇500 ml胃管内注入导泻;将2011年1～7月89例同类患者设为对照组2,在常规处理后以0.2%肥皂水800 ml灌肠;将2011年8月～2012年4月90例同类患者设为观察组,在常规处理后给予开塞露400 ml深部灌肠。结果:观察组患者排便次数显著增加,患者在住院时间、阿托品化时间、并发症、病死率均优于对照组1和对照组2(P<0.05)。结论:开塞露灌肠可有效促进排便,促进肠道内毒物的排泄,减少毒物吸收,提高救治效果。
Objective: To investigate the clinical effect of Kaiseru enema on patients with acute organophosphorus pesticide poisoning. Methods: From April 2010 to December 2010, 89 patients with oral organophosphorus pesticide were enrolled as control group 1. The patients were treated with conventional treatment, ie, gastric lavage plus 20% mannitol 500 ml gastric tube for catharsis; 89 cases of the same type of patients as control group 2, after conventional treatment with 0.2% soapy water 800 ml enema; August 2011 ~ April 2012, 90 cases of similar patients as the observation group, given conventional open caesar 400 ml deep enema. Results: The number of defecation in the observation group was significantly increased. The duration of hospitalization, atropisol time, complications and mortality were all better in the observation group than in the control group 1 and the control group 2 (P <0.05). Conclusion: Kaiseru enema can effectively promote defecation, promote the excretion of intestinal tract poison, reduce the absorption of poison and improve the therapeutic effect.