维生素D_2果糖酸钙注射液为非均匀体系的乳浊液。维生素D_2在油溶液中很稳定,而在此注射液中不稳定,其主要原因在于为非均匀体系乳浊所致,以界面对稳定性的影响最大。乳化剂用量增加维生素D_2稳定性亦降低。根据此注射液不稳定的主要原因,采用了添加油溶性抗氧剂和充以惰性气体的抗氧化措施,结合乳浊液的特点,此种措施是合理的,留样观察证明也是有效的。 Vitamin D_2 fructose calcium injection for non-uniform emulsion system. Vitamin D 2 in the oil solution is very stable, but in this injection instability, mainly due to non-uniform system due to opacity, the interface of the stability of the greatest impact. Increasing the amount of emulsifier vitamin D 2 stability also decreased. According to the main reason for the instability of the injection, the use of oil-soluble antioxidant and filled with inert gas antioxidant measures, combined with the characteristics of the emulsion, this measure is reasonable, sample observation proved to be effective.