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由于ACTH和考地松对风湿样关节炎有效,故人们认为此病是肾上腺皮质机能不足或失调的结果。可是现有的事实不能证实这一点。也没有根据认为,滑膜易被肾上腺皮质激素穿过,或氢化考地松在周围和组织中的代谢障碍是风湿样关节炎的病因。在风湿样关节炎和阿狄森氏病均曾发现垂体前叶的粘液样细胞中有典型的组织化学改变。在风湿样关节炎病人,与球蛋白增多有关的絮状试验呈阳性,醣代谢有若干障碍,即一般认为属于肝功能障碍表现的变化。葡萄糖以及果糖的糖曲线呈延迟型,证明肝糖元分解减少。白蛋白减少,而纤维蛋白原及球蛋白增多,尤其是2号甲种和丙种球蛋白。2号甲种球蛋白-白蛋白系数降低,此点被认为是风湿病和风湿样关节炎在复发期间的特
Because ACTH and cortisone are effective for rheumatoid arthritis, it is thought that the disease is a result of inadequate or dysfunctional adrenal cortex. However, the existing facts do not confirm this point. It is also not at all argued that the synovial membrane is susceptible to adrenal cortical hormones or that the metabolism of cortisone in and around the tissue is the etiology of rheumatoid arthritis. In rheumatoid arthritis and Addison’s disease were found in the anterior pituitary myxoid cells typical histochemical changes. In patients with rheumatoid arthritis, the flocculation test associated with an increase in globulin is positive and there are several obstacles to glycometabolism, a change that is generally considered to be a manifestation of liver dysfunction. Glucose and fructose sugar curve was delayed type, glycogen decomposition proved to reduce. Reduced albumin, while fibrinogen and globulin increased, especially 2 # and gamma globulin. 2 A hypoglobulin - albumin coefficient decreased, this point is considered rheumatoid arthritis and rheumatoid arthritis in the recurrence of special