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目的评价重症手足口病(HFMD)患儿心肌酶谱、心肌肌钙蛋白I(cTnI)和心电图改变的临床意义。方法 15例重症HFMD,在治疗前后患儿行心肌酶谱、cTnI及常规12导联心电图检查。结果所有患儿治疗前心肌酶均有异常,cTnI升高10例(66.7%),心电图异常14例(93.3%),以ST-T改变及T波低平为主;治疗后上述指标均明显改善(P<0.01)。结论重症HFMD患儿存在不同程度的心肌损害。
Objective To evaluate the clinical significance of myocardial enzymes, cardiac troponin I (cTnI) and electrocardiogram (ECG) in children with severe hand-foot-mouth disease (HFMD). Methods 15 cases of severe HFMD, before and after treatment of myocardial enzymes in children, cTnI and conventional 12-lead ECG. Results All patients had abnormal myocardial enzymes before treatment. Elevated cTnI in 10 patients (66.7%) and abnormal electrocardiogram in 14 patients (93.3%) were mainly caused by ST-T changes and T wave depression. All the above indexes were obvious after treatment Improve (P <0.01). Conclusion There are different degrees of myocardial damage in children with severe HFMD.