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应用榄香烯乳膀胱内灌注治疗与预防膀胱肿瘤复发18例,并与同期膀胱内灌注丝裂霉素C16例,对照组13例,进行随访观察。结果表明,肿瘤复发率,榄香烯乳组和丝裂霉素组明显低于对照组(5.9%、6.25%比30.7%),同时观察应用榄香烯乳者,在治疗前后做淋巴细胞转化试验平均值分别为55.4%和69.7%(P<0.05),淋巴细胞转化率显著增长,而丝裂霉素组治疗前后平均值分别为52.3%和54.5%,无明显差异。榄香烯乳是国内新研制生产的一种无细胞毒抗癌新药,初步应用于治疗与预防膀胱肿瘤复发,近期疗效显著,且无明显副作用,尤其无骨髓抑制。
Elemene intravitreal infusion treatment and prevention of bladder tumor recurrence in 18 cases, with the same period of intravesical instillation of mitomycin C16 cases, control group of 13 patients were followed up. The results showed that the tumor recurrence rate was significantly lower in the elemene and mitomycin groups than in the control group (5.9%, 6.25% vs. 30.7%). Elemene was also observed in the The mean values of lymphocyte transformation before and after treatment were 55.4% and 69.7% respectively (P <0.05), and the lymphocyte transformation rate increased significantly, while the average value of mitomycin group before and after treatment was 52.3 % And 54.5%, no significant difference. Elemene is a new non-cytotoxic anticancer drug developed and produced in China. It has been initially applied to the treatment and prevention of bladder tumor recurrence and has obvious short-term curative effect with no obvious side effects, especially without myelosuppression.